Phosphorylation of Vesicular Stomatitis Virus Phosphoprotein P Is Indispensable for Virus Growth

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Phosphorylation of vesicular stomatitis virus phosphoprotein P is indispensable for virus growth.

The phosphoprotein (P) of vesicular stomatitis virus (VSV) is an essential subunit of the viral RNA-dependent RNA polymerase (RdRp) complex. It is phosphorylated at two different domains. Using defective interfering (DI) RNA or minigenomic RNA templates, we previously demonstrated that phosphorylation within the amino-terminal domain I is essential for transcription, whereas phosphorylation wit...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 2004

ISSN: 0022-538X,1098-5514

DOI: 10.1128/jvi.78.12.6420-6430.2004